It is a very valuable contribution which brings together many interesting metallo- proteins which have provided fascinating insights into the elegance and beauty of so many life processes. The extreme ation contrasts with the treatment of Saccharomyces diversity of form in the fungi has always been a cerevisiae, for example, which because of its ideal source of inspiration for mycologists. Mathematical modelling of fungal growth. . The impetus for this work tion of fungi and that it provides the reader with stems from our perception that the coverage of adequate source references for further information. Part Four: Coordination of growth and division. His interest is in structural roles of metal ions in proteins and in the development of novel structural determination methods.
The text has been assembled under joint authorship of two of the contributing authors and presents a general review of the subject areas chosen. The contents are split into five parts: the growing fungus; architecture of fungal cells; metabolism and genetic regulation; coordination of growth and division; differentiation. The material has generally been chosen well and is wide ranging and detailed; relationships with systems appertaining to yeasts are usually given for comparison. Part four deals with tip growth and kinetics and mathematical modelling of filamentous growth. Asexual sporulation in higher fungi. Kinetics of filamentous growth and branching. There are some omissions, however.
The interests of both are clearly reflected in the organization and selection of material. The E-mail message field is required. This area of eukaryotic biology has been fairly neglected. Sexual reproduction of higher fungi. The first part deals with the growing fungus and mycelial interconnectedness, a phenomenon unique to filamentous organisms.
Rather they emphasize the metals Au, Cd, Ca, Co, Cu, Fe, Hg, Mg, Mn, Na, Ni, K, Pt, V, Zn which function through interaction with proteins or nucleic acids and about which there is most knowledge appropriate for the purpose of outlining principles. Each page is presented in a two column format. The other eight chapters constitute the real core of the book in which the organizing principles with which the authors are concerned are defined at the beginning of each chapter and then exemplified in the text. Thus 5 and 6 consider the selection and entry of metal ions into living organisms or cells, 7 and 8 consider how metals bind to biomolecules, while 9, 10, 11 and 12 focus on the major roles of metal ions in biological systems ie electron transport, substrate binding and activation, atom- and group-transfer chemistry, and the timing of metal properties to achieve specific functions. Similarly, the use of mercury in the treatment of syphilis, of iron in that of anemia and of magnesium as an intestinal laxative, have a long history. Both authors are well known in the field of bioinorganic chemistry. It is modestly priced and represents good value.
University Science Books, Mill Val ley, Cal i fornia. This book is about the growth and differentiation processes underlying the growth and differentia- of filamentous fungi. This is timely in view of the many recent advances that have been achieved through the application of new cytological, biochemical, genetic, and molecular techniques to the study of filamentous fungi. This book is properties for genetic analyses, has established concerned mainly with those systems that have itself as the model eukaryote for the analysis of the been well characterized from the biochemical, cell cycle, and basic studies of biochemical and physiological or genetic points of view. Moreover, there is no mention of penicillin production, for example, or of secondary metabolism, in general, anywhere in the book.
The writing is clear and each chapter is clearly illustrated. Published work has long since appeared describing the fatty acid synthetase complexes in Neurospora and Aspergillus, not to mention Lynen's earlier pioneering work on the yeast enzyme. Berg is a professor of biophysics and biophysical chemistry at Johns Hopkins Univer- sity School of Medicine. F Vella The Growing Fungus Edi ted by N A R Gow and G M Gadd. Part Three: Metabolism and genetic regulation.
This situ- only in diversity to the insects. The opening and closing chapters are, respectively, an overview and a discussion of the frontiers of bioinorganic chemistry. Metabolism in- cludes chapters on exoenzymes, transport, signal transduction and intermediary but not secondary pathways; genetics and molecular biology are covered here. The impetus for this work tion of fungi and that it provides the reader with stems from our perception that the coverage of adequate source references for further information. Surely this represents a serious omission, since filamentous fungi, together with filamentous bacteria, provide the source of virtually all the clinically useful antibiotics.
Notwithstanding all this, most biochemistry textbooks in current use tend to treat the inorganic elements as interesting but largely alien to their major interest- - one which focuses on the organic chemistry of small and large biomolecules. They make no attempt to consider all the inorganic elements that are essential for life. Fatty acid and lipid biosynthesis is dis- missed in a paragraph p 221 , and even this is partially negated by an erroneous version of fatty acid formation using CoA derivatives in Fig. Responsibility: edited by Neil A. I found myself using the extensive index very frequently in the early part of reading the book. This book builds a bridge between the arbitrary division of biochemistry into bioorganic and bioinorganic camps. This book is properties for genetic analyses, has established concerned mainly with those systems that have itself as the model eukaryote for the analysis of the been well characterized from the biochemical, cell cycle, and basic studies of biochemical and physiological or genetic points of view.
A delight for me are the three dozen or so ribbon diagrams of the tertiary structure of as many metalloproteins. The Growing Fungus By M. Abstract: This book brings together recent advances in the cell biology, physiology and genetics of growth and differentiation of filamentous fungi. Another criticism is that electron micrographs are generally poorly reproduced, with little contrast. Their production, too, presumably aids the survival of these organisms in some way and therefore should have been discussed in this book.